Lymphoma: Dual-Targeting CAR T Shows Safety, Efficacy
TOPLINE: In a first in-human study, KITE-363, an anti-CD19/CD20 chimeric antigen receptor (CAR) T-cell therapy, showed high rates of response in patients with highly refractory large B-cell lymphoma (LBCL). The bicistronic, autologous CAR T-cell therapy, designed to prevent CD19 escape through the upfront targeting of CD19 and CD20…
The Download: gambling with humanity’s future, and the FDA under Trump
This is today’s edition of The Download, our weekday newsletter that provides a daily dose of what’s going on in the world of technology. Tech billionaires are making a risky bet with humanity’s future Sam Altman, Jeff Bezos, Elon Musk, and others may have slightly different goals…
Tech billionaires are making a risky bet with humanity’s future
“The best way to predict the future is to invent it,” the famed computer scientist Alan Kay once said. Uttered more out of exasperation than as inspiration, his remark has nevertheless attained gospel-like status among Silicon Valley entrepreneurs, in particular a handful of tech billionaires who fancy themselves the chief architects of humanity’s future. …
Judge denies Mahmoud Khalil’s release after Trump admin submits new filing
A federal judge has declined to release Columbia University alumnus Mahmoud Khalil from federal detention after the Trump administration submitted a last-minute filing. Why it matters: The administration’s tug-of-war with courts over Khalil represents a historic test for immigrants’ speech rights – namely, those of permanent residents – particularly where they concern...
Axelrod on RFK Jr.’s vaccine moves: ‘Genuine catastrophe in the making’
Democratic political strategist David Axelrod on Friday condemned changes Health and Human Services Robert F. Kennedy Jr. made to a key vaccine advisory committee. Kennedy earlier this week fired all 17 members of the Centers for Disease Control and Prevention’s (CDC) Advisory Committee on Immunization Practices (ACIP) and replaced them with eight of his own…
Kennedy’s HHS Sent Congress ‘Junk Science’ To Defend Vaccine Changes, Experts Say
A look inside the Department of Health and Human Services document citing vaccine misinformation that could influence congressional perceptions…
KFF Health News’ ‘What the Health?’: RFK Jr. Upends Vaccine Policy, After Promising He Wouldn’t
Health and Human Services Secretary Robert F. Kennedy Jr. this week did something he had promised not to do: He fired every member of the scientific advisory committee that recommends which vaccines should be given to whom. And he replaced them, in some cases, with vaccine skeptics…
SII, DNDi partner for expanding human trials for dengue treatment
The collaboration will be instrumental in advancing clinical development of a dengue monoclonal antibody in Brazil and potentially other endemic countries in Southeast Asia, with a focus on making treatment affordable and accessible, SII Executive Director Dr. Prasad Kulkarni said…