Structural characterization of influenza group 1 chimeric hemagglutinins as broad vaccine immunogens
Proceedings of the National Academy of Sciences, Volume 122, Issue 7, February 2025. SignificanceInfluenza virus group 1 chimeric hemagglutinin (cHA) vaccines are in human clinical trials as universal influenza vaccine candidates. Here, we determined crystal and electron microscopy structures of group 1 cHAs cH5/1, cH8/1, and cH11/1 with …Spatial population dynamics of bacterial colonies with social antibiotic resistance
Proceedings of the National Academy of Sciences, Volume 122, Issue 7, February 2025. SignificanceInteractions between bacteria are common, particularly in the crowded surface-associated communities that occur anywhere from natural ecosystems to the human body to medical devices. Antibiotic resistance can be influenced by these “social” …Liver-specific transgenic expression of human NTCP in rhesus macaques confers HBV susceptibility on primary hepatocytes
Proceedings of the National Academy of Sciences, Volume 122, Issue 7, February 2025. SignificanceInfectious diseases are often species specific and difficult to model. However, with current genome editing technologies, we can tailor laboratory species for specific research applications. This work addresses a major barrier in the hepatitis …
Prehistoric Human Footprints and Tracks Hint at a 22,000-Year-Old Transporting Tool
Learn about the tracks and footprints at White Sands National Park in New Mexico, possibly representing the earliest evidence of human-made transportation technology…
First female runner could soon break the 4-minute-mile barrier
On May 6, 1954, Roger Bannister pushed through the finishing tape at Iffley Road track in Oxford, England, and collapsed into the arms of friends after becoming the first human to run a mile in less than four minutes…
NASA Names Stephen Koerner as Acting Director of Johnson Space Center
NASA has selected Stephen Koerner as acting director of Johnson Space Center. Koerner previously served as Johnson’s deputy director. “It is an honor to accept my new role as acting director for Johnson,” Koerner said. “Our employees are key to our nation’s human spaceflight goals. I am continually impressed with what our workforce accomplishes and…FTC asked to implement and enforce clearer rules on digital product ownership
In a letter obtained by The Verge, Wyden pointed out that many consumers don’t realize digital purchases don’t come with the same rights as physical ones. If you buy a book, it’s yours – you can lend it, resell it, or keep it forever. However, digital versions often come with…Read Entire Article…O, Lovely Oysters. What Can You Tell Us About Our Changing World?
MedPage Today) — Who hasn’t read Lewis Carroll’s ode in which sweet, young oysters leave their safe ocean-bed only to be eaten by a wily walrus and his dour human pal? Today, scholars still debate the meaning behind “The Walrus and the Carpenter…
Maine Schools Under Federal Investigation for Allowing Males in Girls’ Sports
The U.S. Department of Education’s Office for Civil Rights has launched an investigation into the Maine Department of Education and a local school district for allowing males to compete in girls’ sports, citing a violation of Title IX. President Donald Trump’s recent executive order, “Keeping Men Out of Women’s Sports,” threatens to withdraw federal funding…