OGG1S326C variant frequent in human populations facilitates inflammatory responses due to its extended interaction with DNA substrate

Proceedings of the National Academy of Sciences, Volume 122, Issue 19, May 2025.
SignificanceOGG1S326C, a variant widely recognized as a risk factor for various malignancies and other diseases, has drawn significant attention due to its high prevalence (~20% in Caucasians and ~40 to 60% in Asians) in human populations…
Read More